pharm GRM week #9 (brief)

Week 9-Chapter 27

1. What are anticoagulants?
a. inhibits the action or formation of clotting factors thus preventing clots from forming

2. What are antiplatelet drugs?
a. prevent platelet plugs from forming by inhibiting platelet aggregation which is beneficial for preventing heart attacks and strokes

3. What do thrombolytic drugs do?
a. break down clots which have already formed

4. Why is frequent monitoring not necessary with LMWH?
a. low molecular weight heparins have a predictable anticoagulant response

5. How does warfarin work?
a. inhibits the four vitamin K-dependent clotting factors to prevent clot formation

Week 9-Chapter 28

1. How is cholesterol used in the body?
a. used to make steroid hormones, cell membranes, and bile acids

2. How doe statins lower serum cholesterol levels?
a. decrease rate of cholesterol production

3. What is rhabdomyolysis?
a. breakdown of muscle protein leading to myoglobinuria (urinary elimination of the muscle protein myoglobin

4. When assessing liver enzymes, which are it most important to assess when a patient is on statins?
a. activity of CYP3A4 in the liver to metabolize statins